A genomic study of human and selected nonhuman primate centromeres has revealed their unimaginable diversity and speed of evolutionary change. Although centromeres are vital to proper cell replication ...

Centromeres are regions of DNA where the cell’s machinery grabs each chromosome and pulls it into the two daughter cells. Centromeres are essential for accurate chromosome segregation in every ...

A research team has clarified a mechanism of how retrotransposons, genetic elements that can 'jump around' chromosomes and are known drivers of evolution, preferentially insert in the centromere. A ...

Two different types of centromeres evolved from a monocentromere, a macro-monocentromere in Cha. luteum and a holocentromere in Chi. japonica. Micrographs show mitotic chromosomes. The centromere is ...

The Portuguese island of Madeira is home to six different chromosomal races of mice, each with dramatically reduced diploid chromosome numbers compared to mice elsewhere. This striking diversity, ...

The complete assembly of each human chromosome is essential for understanding human biology and evolution. Using complementary long-read sequencing technologies, we complete the first linear assembly ...

Six years ago, when Glennis Logsdon was a graduate student, everyone assumed that centromeres had conserved sequences and structures given their essential role in divvying up genetic material. “We had ...

Published in Nature, researchers at the University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center report a ...

PITTSBURGH, June, 3, 2026– Published today in Nature , researchers at the University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center ...