New Salk Institute research reveals how aging brains accumulate iron, leading to neuronal vulnerability and diseases like ...

While early in life, the accumulation of iron appears to have little effect on neuron function, later in life, it can ...

Neurodegenerative diseases affect tens of millions of people worldwide. Among these, Alzheimer's and Parkinson's diseases are the most common; in the United States alone, the Alzheimer's Disease ...

Iron deficiency remains the most prevalent micronutrient disorder worldwide, with profound implications for host defence. Beyond its classical role in haemoglobin synthesis and oxygen transport, iron ...

Iron is essential for numerous cellular processes, including oxygen transport, DNA synthesis and energy metabolism. Macrophages are central regulators of systemic and local iron homeostasis: they ...

The duplication and division of cells is critical to keeping all multicellular organisms alive. But the opposite process is equally important: cell death. Controlled death of cells, or programmed cell ...

Fukuoka, Japan—The duplication and division of cells is critical to keeping all multicellular organisms alive. But the opposite process is equally important: cell death. Controlled death of cells, or ...

A new fluorescent reporter capable of visualizing biologically active iron and oxygen inside living cells at single-cell resolution has been developed, as reported by researchers from Science Tokyo.

Neurodegenerative diseases affect tens of millions of people worldwide. Among these, Alzheimer's and Parkinson's diseases are the most common; in the United States alone, the Alzheimer's Disease ...

Excess levels of an mineral responsible for healthy blood and brain function may raise the risk of Parkinson's and dementia, ...

Researchers have identified a new process, 'chronoferroptosis', where excess iron in neurons reduces their resilience to stress, increasing vulnerability to neurodegenerative diseases. This discovery ...