A dosage formula has been derived from a retrospective analysis of carboplatin pharmacokinetics in 18 patients with pretreatment glomerular filtration rates (GFR) in the range of 33 to 136 mL/min.
A pharmacokinetic–pharmacodynamic study was carried out to investigate the feasibility and potential importance of therapeutic monitoring following high-dose carboplatin treatment in children.
Non-small cell lung cancer (NSCLC) is the leading cause of cancer death worldwide. Single and two-drug chemotherapeutic regimens have translated into modest increases in life expectancy, so the ...
SAN ANTONIO — The addition of carboplatin to a standard neoadjuvant chemotherapy regimen significantly improves disease-free or event-free survival in patients with early-stage triple-negative breast ...
Platinum-associated adverse events were more likely in patients with impaired kidney function assessed by serum creatinine and cystatin C -- warranting judicious adjustment of platinum chemotherapy ...
Results of two Chinese phase 3 trials presented at this year’s San Antonio Breast Cancer Symposium (SABCS) 2025 provide strong support for adjuvant carboplatin in early-stage triple-negative breast ...
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