Colesevelam (Welchol), a specifically-engineered, non-absorbed polymer that binds bile acids in the intestine thereby impeding their resorption, is approved as an adjunct to diet and exercise to ...

Recently published study results showed that the bile acid sequestrant IW-3718 reduced heartburn and regurgitation symptoms in patients with refractory GERD. Further, the 1,500 mg twice-daily dose of ...

GSK’s linerixibat is currently under regulatory review in the US, Europe, and China, amongst other regions.

Now that colesevelam (WelChol), a bile acid sequestrant (BAS), has been shown to decrease hemoglobin A 1c (HbA 1c), should it be the agent of choice (rather than ezetimibe [Zetia]) in diabetic ...

BOSTON--(BUSINESS WIRE)--Ironwood Pharmaceuticals, Inc. (NASDAQ: IRWD), a leading GI-focused healthcare company, today announced that it has reached alignment with the U.S. Food and Drug ...

There's been quite a bit of "noise" in the cholesterol category within the past year -- statins being recalled or relabeled due to safety concerns and future "super statins" now being called into ...

Livdelzi (seladelpar) is a medicine that can treat primary biliary cholangitis (PBC) by reducing the amount of bile in your body. It does this by signaling the body to stop making bile acid. People ...

Results inconsistent for association with bile acid sequestrant use depending on diabetes and liver disease status. HealthDay News — The use of cholesterol absorption inhibitors is associated with a ...