In bacteria, to start DNA replication, two replisomes attach to the DNA at a set origin point and head in opposite directions along the loop of DNA, copying DNA until they meet on the other side.

Journal reference: Sanders, S., et al. (2023) Beyond the average: An updated framework for understanding the relationship between cell growth, DNA replication, and division in a bacterial system.

The FDA has accepted GSK's application for priority review of gepotidacin, a first-in-class antibiotic for uncomplicated ...

That said, this study assessed the accuracy of a bacterial DNA polymerase. The researchers created a miniature laboratory where DNA polymerase from Escherichia coli went through one round of ...

They designed a semi-automatic mini-laboratory to enable a single round of replication of a 1000-nucleotide-long engineered DNA fragment, during the weightless phase of parabolic flight.

Albicidin has a different mode of action than other antibiotics. Known as a peptide antibiotic, it inhibits DNA gyrase, essential enzymes that help progress bacterial DNA replication.

Cyanobacteria transposons have hairpin-shaped telomers, which, as Peters puts it, “solves the replication problem” of a double-end break, allowing the polymerase to wrap around the end of the ...

During the process of bacterial DNA replication, DNA Polymerase, which catalyze the synthesis of DNA, plays an indispensable role. In order to keep DNA Polymerase III sliding along, a protein ...