Melissa tested for the BRCA2 gene mutation after her mom's breast cancer diagnosis to be proactive about her breast and ovarian health.

Melissa tested for the BRCA2 gene mutation after her mom's breast cancer diagnosis to be proactive about her breast and ovarian health.

Inherited mutations in the gene BRCA2 significantly increase the risk of carriers to breast and ovarian cancers. BRCA2, a crucial player in the body's DNA repair system, aids in repairing damaged DNA.

Researchers analyzed DNA samples from 6,272 women with BRCA2 mutations in a two-stage genome-wide association study. The chromosome 10 variant identified in the study, near the gene ZNF365, decreased ...

Mathew Knowles gets candid about surviving breast cancer and living with the BRCA2 gene mutation. Mathew Knowles is honoring Breast Cancer Awareness Month by opening up about his own experience as ...

The BRCA gene mutation is most commonly associated with breast cancer. But it can also potentially affect one's risk for other cancers. Here's what to know.

Women with breast cancer who were also carriers of the BRCA1 or BRCA2 mutation and received textured breast implants as part of their reconstructive surgery after mastectomy were 16 times more ...

Medically reviewed by Archana Sharma, DO The exact cause or causes of triple-negative breast cancer are unknown, but researchers have linked it to mutations in the BRCA1 and BRCA2 genes. They also ...

Breast cancer types, staging, diagnosis, treatment, and survivorship are complex, but understanding them helps patients make ...

People carrying BRCA1 and BRCA2 gene mutations are at high risk of developing breast and ovarian cancer. Researchers have found that changes occur in the immune cells of breast tissue in carriers ...

BRCA1 mutations were detected in 20 (45.5%) of 44 families with ovarian cancer and 12 (75%) of 16 families with both breast and ovarian cancer in a single individual. Significantly fewer BRCA2 ...

In Ireland, one in 400 people (0.25%) is estimated to carry a harmful BRCA1 or BRCA2 gene mutation. People with a strong family history of breast or ovarian cancer are most likely to be referred for ...