Nature

Crystal structure of a bacterial homologue of glucose transporters GLUT1–4

Figure 1: The structure of XylE bound to d-xylose has an outward-facing, partly occluded conformation. Figure 2: Recognition of d-xylose by XylE. To examine the role of these residues in d-xylose ...
Phys.org

Novel method reveals glucose channeling, charting the fine structure of energy metabolism inside active cells

In a scientific first, researchers from Vanderbilt University and the University of California, San Diego, have generated a high-resolution metabolic "map" of how cells orchestrate glucose processing, ...
Nature

Blocking the utilization of glucose induces the switch from senescence to apoptosis in pseudolaric acid B-treated human lung cancer cells in vitro

Pseudolaric acid B (PAB), a diterpene acid isolated from the root bark of Pseudolarix kaempferi Gordon, exerts anti-tumor effects in several cancer cell lines. Our previous study showed that PAB ...
EurekAlert!

Pioneering new method reveals glucose channeling, charting the fine structure of energy metabolism inside active cells

3D electron tomography reveals glycogen particles (purple) clustered on the surface of lipid droplets (yellow), closely associated with endoplasmic reticulum membranes (blue) and mitochondria (red), ...