KLF2 activity and impaired interferon signaling contribute to HIV-1 persistence by restricting antiviral immunity in infected CD4 T cells during early infection.

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a ...

Ankylosing spondylitis (AS) is increasingly recognized as an independent risk factor for premature myocardial infarction (MI) ...

A new study has found that ORC plays a broad, unexpected role in regulating human cell gene expression and chromatin ...

Single-cell technology has revolutionized the field of biological research by enabling the analysis of individual cells, providing unprecedented insights into cellular heterogeneity and function. More ...

The non-coding genome, once referred to as "junk DNA," is now understood to be a fundamental regulator of gene expression and ...

DEFND-seq originally came about from a mistake in the lab. As scientific director of the Sulzberger Columbia Genome Center, Sims observed many experiments where an existing test, called ATAC-seq ...

Touching Base is the dynamic podcast series from the editors of GEN. Each episode features a rotating case of senior editors—including John Sterling, Kevin Davies, Julianna LeMieux, Alex ...