APC is a tumor suppressor gene and is inactivated in 80% of colorectal cancers. The team found that combined inactivation of SOX9 and APC resulted in more invasive tumors than APC inactivation alone.

New drug discovered to treat bowel cancer. Briton researchers have recently discovered a new drug target for bowel cancer ...

Colorectal cancer (CRC) is a significant global health concern, originating from precancerous polyps in the colon or rectum and progressing through ...

Researchers have discovered an unusual case where two well-known cancer-related mutations-APC and KRAS-coexisted in a woman with familial adenomatous polyposis (FAP) and a history of endometrial ...

Genes get passed down from parents, determining traits such as eye color and height as well as risk for certain diseases. And while cancer-linked genes such as BRCA1 and TP53 are relatively ...