LaBonne is president of the Society for Developmental Biology and the Erastus Otis Haven professor of molecular biosciences at Northwestern University. Imagine a world without lifesaving medicines, ...

Monash University scientists have challenged the conventional wisdom that biological patterns are explained by physical constraints. In a study published today in Science, the researchers present ...

In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal testing in biomedical research. Central to these ...

Animal models are established, important tools for preclinical safety and efficacy testing. Companies are advancing more “humanized” models to better reflect human responses, while at the same time ...

Too often, preclinical successes are followed by clinical failures. And all clinical failures hurt. Perhaps the most painful failures occur in trials that require large patient populations and long ...

In a recent study published in the Frontiers in Neuroendocrinology journal, researchers assessed the impact of hormonal contraceptives (HC) on the brain and stress. Hormonal contraceptives have ...

Preclinical testing is vital for assessing the safety profiles and potential efficacy of new therapeutics in development. Animal testing is one of two routes usually selected for the preclinical stage ...

I recently read a highly-detailed, comprehensive, science-based report called The Research Modernization Deal 2021. It unambiguously shows that numerous experiments on nonhuman animals (animals) fail ...