Key proteins implicated in neurodegenerative diseases are alpha synuclein and tau. Tau aggregation into neurofibrillary tangles, along with amyloid-beta aggregation into plaques, is a hallmark of ...

A rare genetic variant reveals mitochondria can kick-start Parkinson’s, linking oxidative stress to alpha-synuclein clumps ...

The sunbird Syn (TM) assay accurately classified Parkinson's disease-positive blood samples with 81% accuracy through the direct detection of EV-bound aggregated alpha-synuclein proteins -- -- With no ...

Amsterdam, NL, November 13, 2019 - Aggregates of the protein alpha-synuclein arising in the gut may play a key role in the development of Parkinson's disease (PD). Investigators are testing the ...

Studies have uncovered that abnormalities in the alpha-synuclein protein are likely a causal factor for numerous diseases, including Parkinson’s disease, multiple system atrophy (MSA), dementia with ...

In the brain, alpha-synuclein is known for forming clumps called Lewy bodies, which damage brain cells and lead to diseases ...

Multiple system atrophy (MSA) is a neurodegenerative disorder characterized by the aggregation of alpha-synuclein in the brain. Now, scientists have developed a radioligand that facilitates the ...

Millions of people in the United States are affected by Parkinson’s disease and Lewy Body Dementia (LBD). These are both ...

Oral bacteria that migrate to the gut can generate metabolites that reach the brain and accelerate Parkinson’s disease.

This therapy is one of a few drugs in mid-to-late-stage development for Parkinson’s that has displayed disease-modifying ...