Reactions that completely break carbon-carbon double bonds have particular transformative power in synthesis. Ozonolysis, which splits one alkene into two carbonyl compounds using trioxygen, is widely ...
The novel method uses a recycling photoreactor with an immobilized photosensitizer, coupled with a high-performance liquid chromatography technology, to enable efficient and sustainable synthesis of Z ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, No. 23 (June 10, 2014), pp. 8368-8373 (6 pages) Despite recent advances of asymmetric synthesis, the ...
A new cobalt catalyst designed by Paul Chirik and coworkers at Princeton University gives chemists two mechanisms for the price of one. The team’s alkene hydrogenation reaction runs differently ...
Researchers have discovered a new way to drive chemical reactions that could generate a wide variety of azetidines -- four-membered nitrogen heterocycles that have desirable pharmaceutical properties.
Chemists have for a long time been interested in efficiently constructing polyenes - not least in order to be able to use them for future biomedical applications. However, such designs are currently ...
Chemical structures called cyclopropanes can increase the potency and fine-tune the properties of many drugs, but traditional methods to create this structure only work with certain molecules and ...
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