Profiling kinase inhibitors is a critical step in the development of chemical probes or kinase drugs. The ability to generate an inhibitory profile of a compound across a broad collection of kinases ...
In a recent study posted to the bioRxiv* preprint server, researchers discovered compounds able to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) macrodomain 1 (Mac1) and ...
The development of new therapeutics targeting protein kinases is crucial in the fight against diseases like cancer. Kinase drug discovery programs rely on the precise characterization and screening of ...