According to the US Centers for Disease Control and Prevention, two doses of the MMR (measles, mumps and rubella) vaccine are 97% effective at preventing measles, while one dose is 93% effective. It is uncommon for someone who is fully vaccinated to develop measles, although the first breakthrough case of 2025 was recently detected in Colorado.

While measles symptoms typically resolve in a few weeks, the virus can cause pneumonia, making it difficult for patients, especially children, to get oxygen into their lungs. It may also lead to brain swelling, which can cause lasting damage, including blindness, deafness and intellectual disabilities.