The Red Sox suffered one of their worst losses of 2025, falling in 11 innings Tuesday despite Nathaniel Lowe's heroics in the ninth.

The Red Sox concocted a plan before their series against the Orioles and stuck to it, manager Alex Cora said after a frustrating 4-3 loss at Fenway Park on Tuesday night.

The Red Sox had won 10 of 12 games and Roman Anthony hit a double in the ninth inning against the Padres to tie the game 4-4. Simmons hit send shortly before the Padres scored in the 10th to win the game. They have dropped seven of 10 games since he tweeted this:

The Baltimore Orioles blew a late lead, but then beat the Boston Red Sox 4-3 in 11 innings on Samuel Basallo's RBI.

Boston left the bases loaded in the eighth, ninth and 10th innings Tuesday, squandering crucial opportunities to score.

The 21-year-old Orioles star has seen some of the progress Red Sox rookie Kristian Campbell has made since being demoted to Triple-A Worcester.

Cora made good on that final promise on Monday night, as Lowe came in to pinch-hit in the ninth inning against Baltimore Orioles closer Yennier Cano. He drew a seven-pitch walk and scored on a Jarren Duran double, but Boston still lost 6-3.

The Orioles have won three consecutive series against teams in playoff position after sweeping the Red Sox in a wild game Tuesday.

BOSTON — Over the course of a long season, there are often multiple candidates for worst loss of the year. Only a few days ago, the Red Sox squandered a two-run lead with six outs to go. And the fact that they’ve been walked off 11 times on the road is a reminder that there’s plenty of competition for the title.

The term "gut punch" might be overused on occasion, but it assuredly applied to the Boston Red Sox's 4-3 loss to the Baltimore Orioles on Tuesday night. The Red Sox loaded the bases in the eighth inning with no outs,